基于文献计量学和可视化技术分析地舒单抗及双膦酸盐治疗骨质疏松性骨折的研究现状及趋势

目的:随着老龄化进程加速,骨质疏松性骨折(osteoporotic fracture,OPF)的研究越来越受到人们的关注.本研究的目的是研究全球地舒单抗、双膦酸盐治疗OPF的现状和趋势.方法:检索1994-2018年双膦酸盐和OPF相关文献,检索自Science Citation· Index-Expanded Web...

Research status and future trends of bibliometrics and visualization technology for Xgeva and bisphosphonates in the treatment of osteoporotic fracture

OBJECTIVE To explore current status and future trend in the emerging field of osteoporotic fracture(OPF).METHODS The relevant literatures of OPF were retrieved from Science Citation Index-Expanded Web of Science from 1994 to 2018.Bisphosphonates were employed for collating the source data.For visualizing the OPF researches, VOS viewer software was utilized for analyzing bibliographic association, co-authorship, co-occurrence and publishing trends.RESULTS A total of 3,879 reports were included.The numbers of publications and research hotspots were rising annually.The United States had the highest contribution rate to global researches.Osteoarthritis and cartilage periodicals showed the highest publishing rate.University of Sheffield, University of California, San Francisco and University of Liege were the most productive institutions.Research fell into four categories of mechanism, animal, clinical trial and tissue engineering.Clinical research in this field was expected to be the next hot topic.CONCLUSION According to current trends, the number of OPF publications shall continuously increase.Application of bisphosphonates is probably a hot topic in OPF and drug developments.