血小板相关参数在脓毒症中临床意义的研究进展

脓毒症是一种宿主对感染免疫反应失调导致的器官功能障碍综合征.脓毒症具有高发病率和高病死率的特点,当患者出现血小板减少时其病死率进一步增加.近年来,血小板在脓毒症病理生理中的作用已经成为新的关注焦点.血小板相关参数,包括数量、功能、平均血小板体积、血小板分布宽度、未成熟血小板及血小板生成素等与脓毒症的严重程度及预后密切相...

Advances in the clinical significance of platelet-related parameters in sepsis

Sepsis is an organ dysfunction syndrome caused by the host's immune response to infection,and it is also one of the most common diseases in ICU.Sepsis has the characteristics of high morbidity and high fatality rate.When the patient has thrombocytopenia,the fatality rate further increases.In recent years,the role of platelets in the pathophysiology of sepsis has become a new focus of attention.Platelet-related parameters,including number,function,average platelet volume,platelet distribution width,immature platelets and thrombopoietin,are closely related to the severity and prognosis of sepsis.Therefore,timely monitoring of platelet-related parameters not only helps clinicians accurately identify patients with high-risk sepsis,but also helps judge the prognosis of the disease.This article reviews the clinical significance of platelet-related parameters in patients with sepsis.