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Use of assisted reproductive technology to separate sperm from human immunodeficiency virus infected men resulting in pregnancy among serodiscordant couples
Authors:Alessandro Schuffner  Ana Paula Lisboa  Vinicius Bonato da Rosa  Monica Maria Gomes da Silva
Affiliation:1. Ex-fellow at Jones Institute for Reproductive Medicine, USA; Obstetrician and Gynecologist Specialist; Physician at Conceber, Reproductive Medicine Center, Curitiba, PR, Brazil;2. Obstetrician and Gynecology Specialist; Reproductive Endocrinology Specialist; Physician at Conceber Reproductive Medicine, Curitiba, PR, Brazil;3. Biologist and Embryology Specialist; Biologist at Conceber Reproductive Medicine, Curitiba, PR, Brazil;4. Infectious Diseases Specialist (SBI); Neurology Specialist (ABN); Hospital Nossa Senhora das Graças, Infectious Diseases Department, Curitiba, PR, Brazil
Abstract:Due to HIV care improvement, discordant couples more frequently seek help in order to conceive their own biological child. Besides the advance of antiretroviral therapy, unprotected intercourse is not a complete safe option, carrying a low but still present risk of HIV transmission. We report 10 serodiscordant couples in whom the male partner is HIV positive, submitted to sperm washing and intrauterine insemination. The procedure resulted in four pregnancies and no HIV transmission to mother or child was observed. Techniques of assisted reproduction can help HIV discordant couples to conceive biological offspring and is a safer option than unprotected intercourse.
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