杭州市富阳区阿尔茨海默病患病率及其影响因素研究

目的:调查杭州市富阳区≥65岁人口阿尔茨海默病患病率及其影响因素.方法:采用分层随机整群抽样,共调查5483人.调查采用筛查和确诊两阶段法,由精神科医师按照ICD-10诊断标准进行阿尔茨海默病的诊断.结果:查出阿尔茨海默病患者301人,粗患病率为5.5％.阿尔茨海默病患病率随年龄增加而显著增长(Linear-by-Li...

Prevalence of Alzheimer's Disease and Its Risk Factors in Fuyang District of Hangzhou

[Objective]To investigate the prevalence of Alzheimer’s disease( AD) and its risk factors in Fuyang District of Hangzhou. [Method] This study w as conducted among residents aged 65 years old and over in Fuyang District of Hangzhou. In total,5483 participants w ere recruited in this study by stratified random sampling from three levels. All participants w ere screened by AD8. Then,those w ith scores on AD8 ≥2 w ere interview ed w ith experienced psychiatrists. The clinical diagnosis of AD w as made according to the ICD-10. [Result] 301 patients( 5. 5%) w ere diagnosed w ith AD. The prevalence of AD increased consistently w ith advancing age( Linear-by-Linear χ2= 375. 106,P< 0. 001). There were significant association between the prevalence rate of AD and hypertension( OR = 10. 291,95% CI= 7. 862 ~ 13. 471),hyperlipemia( OR = 3. 278,95% CI = 2. 197 ~ 4. 891),and alcohol drinking( OR = 3. 578,95%CI = 2. 302 ~ 5. 563),respectively. [Conclusion] The prevalence of AD in Fuyang District increases w ith age. Alcohol drinking and metabolism-related diseases may be risk factors for AD.