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重症肌无力与细胞因子
引用本文:易芳芳,朱雯华,赵重波.重症肌无力与细胞因子[J].中国临床神经科学,2014(4):470-474.
作者姓名:易芳芳  朱雯华  赵重波
作者单位:复旦大学附属华山医院神经内科,200040
基金项目:上海市科委基金资助项目(编号:11411952200)
摘    要:重症肌无力(MG)是一种以体液免疫介导为主、细胞免疫依赖和补体参与的神经肌肉接头的自身免疫性疾病。研究表明,细胞因子间的平衡紊乱与MG的发病有着重要的关系。因此,深入了解不同细胞因子在MG中的作用可以更加明确MG的发病机制以及对治疗提出新的研究方向。

关 键 词:重症肌无力  自身免疫性疾病  细胞因子

Research Progress of Myasthenia Gravis and Cytokines
YI Fang-fang,ZHU Wen-hua,ZHAO Chong-bo.Research Progress of Myasthenia Gravis and Cytokines[J].Chinese Journal of Clinical Neurosciences,2014(4):470-474.
Authors:YI Fang-fang  ZHU Wen-hua  ZHAO Chong-bo
Institution:Department of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China
Abstract:Myasthenia gravis (MG) is a kind of autoimmune diseases which is mainly caused by the humoral immunity mediation, cellular immunity dependence and the complement involvement, and results in the damage of the neuromuscular transmission. Recent studies have shown that the cytokines balance disturbance has important relationship to the pathogenesis of MG. Extensive studies focusing on the role of various cytokines in MG help us better understand the pathogenesis of MG, and formulate the new treatment scheme for MG.
Keywords:myasthenia gravis  autoimmune diseases  cytokine
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