| 大脑巢蛋白的研究进展 |
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| 引用本文： | 韦斌垣,赵伟佳. 大脑巢蛋白的研究进展[J]. 医学综述, 2006, 12(19): 1153-1155 |
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| 作者姓名： | 韦斌垣 赵伟佳 |
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| 作者单位： | 广西医科大学第一附属医院神经内科,南宁,530021 |
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| 摘 要： | 巢蛋白属于一种胚胎性中间丝蛋白,被认为是神经干细胞的标志物之一。巢蛋白被中枢神经系统和周围神经系统大多数增殖活跃的前体细胞所表达,发育成熟的神经系统巢蛋白表达降低。然而不少实验表明,损伤的神经系统巢蛋白表达又重新升高。提示其与提高脑的抗损伤能力有关。
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| 关 键 词： | 脑 巢蛋白 神经干细胞 表达 损伤 |
| 文章编号： | 1006-2084（2006）19-1153-03 |
| 收稿时间： | 2006-04-20 |
| 修稿时间： | 2006-04-20 |
The Progress of Nidogen in Cerebrum |
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| WEI Bin-yuan,ZHAO Wei-jia. The Progress of Nidogen in Cerebrum[J]. Medical Recapitulate, 2006, 12(19): 1153-1155 |
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| Authors: | WEI Bin-yuan ZHAO Wei-jia |
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| Affiliation: | Department of Neurology, the First Hospital Affilisted to Guang Xi Medical University, Nanning 530021, China |
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| Abstract: | Nestin is an embryo intermediate filament protein, which is considered as a marker of nerve stern cell. Nestin is abundantly expressed in the proliferated progenitor cell of the central nervous system and peripheral nervous system, and deficiently expressed in the mature nervous system. However, many exeperim- ents showed that the expression of nestin also gained its high expression after the nervous system injury, which suggested that it high expression maybe related to promote the ability of anti -injury in brain. |
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| Keywords: | Brain Nestin Neural stem cell Expression Injury |
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