| 六味地黄汤生物制剂对小鼠耐寒、耐缺氧及抗疲劳作用的实验研究 |
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| 引用本文： | 丘婷,李天河,吴思,汤佩莲,赵越.六味地黄汤生物制剂对小鼠耐寒、耐缺氧及抗疲劳作用的实验研究[J].广东药学院学报,2011,27(6):621-623. |
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| 作者姓名： | 丘婷 李天河 吴思 汤佩莲 赵越 |
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| 作者单位： | 广东药学院 中药学院,广东 广州,510006 |
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| 基金项目： | 广东省自然科学基金重点项目，广州市科技局项目 |
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| 摘 要： | 目的 观察六味地黄汤生物制剂对小鼠耐寒、耐缺氧、抗疲劳的影响.方法 昆明种小鼠随机分为空白对照组、六味地黄汤阳性对照组及六味地黄汤生物制剂低、中、高(2.4、4.8、9.6 g/kg)剂量组,灌胃给药7d后分别考察小鼠-5℃寒冷的死亡率、常压耐缺氧时间以及负重游泳时间.结果 六味地黄汤生物制剂能明显降低小鼠-5℃...
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| 关 键 词： | 六味地黄汤生物制剂 耐寒 耐缺氧 抗疲劳 |
Effect of Liuweidihuang metabolized by photosynthetic bacteria on cold-tolerance and oxygen deficit-tolerance and anti-fatigue in mouse |
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| QIU Ting,LI Tian-he,WU Si,TANG Pei-lian,ZHAO Yue.Effect of Liuweidihuang metabolized by photosynthetic bacteria on cold-tolerance and oxygen deficit-tolerance and anti-fatigue in mouse[J].Academic Journal of Guangdong College of Pharmacy,2011,27(6):621-623. |
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| Authors: | QIU Ting LI Tian-he WU Si TANG Pei-lian ZHAO Yue |
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| Institution: | (College of Traditional Chinese Medicine,Guangdong Pharmaceutical University,Guangzhou 510006,China) |
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| Abstract: | Objective To investigate the effect of Liuweidihuang metabolized by photosynthetic bacteria（LW-PSB） on murine resistance against cold,oxygen deficit and fatigue.Methods KM mice were randomly divided into five groups,including the negative control group,positive control group（Liuweidihuang metabolized） and three LW-PSB-treated groups（2.4,4.8 and 9.6 g/kg）.After 7 days,stress response was tested.Results LW-PSB obviously shortened the mortality rate of mice at-5 ℃ and lengthened the time of mice at oxygen deficit as well as weight-bearing swimming.Conclusion LW-PSB affords an important role in resistance to cold,oxygen deficit and fatigue in mice. |
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| Keywords: | LW-PSB cold oxygen deficit fatigue |
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