中国人与白种人鼻咽癌的发病和治疗

对1971—1990年间加拿大不列颠哥伦比亚癌症中心收治的428例鼻咽癌病人的发病和治疗情况进行分析。其中,中国人占303例(71％),白种人116例(27％)。中国人在该省鼻咽癌的年发病率是白种人的64倍,其中又以在中国出生的发病率最高,分别为白种人的104倍和北美出生的中国人的16倍。本组总的5年和10年生存率分别为51％和39％,颈淋巴结阴性的病人5年生存率达64％;而阳性的病人只有44％。鼻咽癌的预后与它的临床分期、病理类型、治疗前有无做颈淋巴结活检,以及性别有关,而与病人的人种和出生地无关。

Nasopharyngeal Carcinoma in Chinese and Caucasians: Analysis of 428 Cases

From 1971 to 1990, 428 cases (303,71%, Chinese and 116, 27%,Cauca- sians) of nasopharyngeal carcinoma (NPC) were treated with radiotherapy at Eiritish Columbia Cancer Agency. The incidence of NPC in the Chinese born in China was 104 times greater than Caucasians and 16 times greater than Chinese bom in North America. The overall survival time for all cases was 51% at 5 years and 39% at 10 years. The survival time was 64% at 5 years for all No cases but is was only 44% in patients with nodal metastasis. The survival time of NPC was related essentially to initial staging, histological grade, sex and pre-irradiation biopsy of neck metastasis and was not significantly related to race or birth place.