| 帕金森病患者脑多巴胺转运体SPECT功能显像研究进展 |
| |
| 引用本文： | 苏敬敬,谢惠君.帕金森病患者脑多巴胺转运体SPECT功能显像研究进展[J].第二军医大学学报,2004,25(7):785-787. |
| |
| 作者姓名： | 苏敬敬 谢惠君 |
| |
| 作者单位： | 第二军医大学长海医院神经内科,上海,200433;第二军医大学长海医院神经内科,上海,200433 |
| |
| 摘 要： | 单光子发射计算机断层显像(single photon emission computed tomography,SPECT)利用特异放射性核素与人脑多巴胺神经元突触前膜脑多巴胺转运体(DAT)的高度亲和性,可进行帕金森病(PD)患者脑DAT显像,目前已广泛应用于PD患者的临床实践.大量研究表明,SPECT对于PD患者的早期诊断、鉴别诊断、病情监测、疗效评价及预后具有重要意义.本文对PD患者脑DAT SPECT显像的图像分析及临床应用研究进展作一综述.
|
| 关 键 词： | 多巴胺转运体 单光子发射计算机断层显像 帕金森病 |
| 文章编号： | 0258-879X(2004)07-0785-03 |
| 修稿时间： | 2003年12月3日 |
Imaging of dopamine transporter with single photon emission computed tomography in patients with Parkinson disease |
| |
| SU Jing-Jing,XIE Hui-Jun.Imaging of dopamine transporter with single photon emission computed tomography in patients with Parkinson disease[J].Academic Journal of Second Military Medical University,2004,25(7):785-787. |
| |
| Authors: | SU Jing-Jing XIE Hui-Jun |
| |
| Institution: | SU Jing-Jing,XIE Hui-Jun * |
| |
| Abstract: | Single photon emission computed tomography(SPECT)can be used in Parkinson desease due to the high affinity of the specific isotope with dopamine transporter(DAT).Nowadays,SPECT imaging in human brain is widely applied in clinical practice of Parkinson disease,such as early diagnosis,differential diagnosis,monitoring,outcome evaluation and prognosis.In this article,a survey is conducted on DAT SPECT imaging and its clinical application in patients with Parkinson disease. |
| |
| Keywords: | dopamine transporter single photon emission computed tomography Parkinson's disease |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《第二军医大学学报》浏览原始摘要信息 |
| 点击此处可从《第二军医大学学报》下载免费的PDF全文 |
