Arsenite decreases CYP3A23 induction in cultured rat hepatocytes by transcriptional and translational mechanisms |
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| Authors: | Noreault Trisha L Jacobs Judith M Nichols Ralph C Trask Heidi W Wrighton Steven A Sinclair Peter R Evans Ronald M Sinclair Jacqueline F |
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| Affiliation: | Veterans Administration Medical Center, White River Junction, VT 05009, USA. |
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| Abstract: | |
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| Keywords: | As2O3, arsenic trioxide BSA, bovine serum albumin CHX, cycloheximide CYP, cytochrome P450 DEX, dexamethasone DMSO, dimethylsulfoxide FeNTA, ferric nitrilotriacetic acid FRET, fluorescence resonance energy transfer GSH, glutathione PNPH, p-nitrophenol hydroxylation PXR, pregnane X receptor RXR, retinoid X receptor TAO, triacetyloleandomycin TBARS, thiobarbituric acid reactive substances UTR, untranslated region |
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