开江县儿童乙型脑炎发病影响因素的病例对照研究

目的:探讨开江县儿童乙脑发病的影响因素,给控制乙脑策略提供科学依据。方法:采用病例配对方法,以开江县2006～2007年发生的乙脑,经血清学确诊的32例,按1:1配对的健康儿童为对照,搜集病例和对照的父母文化、家庭经济收入、室内和室外环境卫生、防蚊灭蚊情况、室内蚊密度、蚊虫叮咬史、养猪情况、监护人乙脑防治知识了解情况、乙脑疫苗免疫史等影响因素信息。结果:单因素分析结果显示,室内卫生好的比例病例组明显低于对照组(χ2=9.3889,P<0.01,OR=0.1250,95%CI:0.0139～0.5317),室外环境卫生好的比例病例组明显低于对照组(χ2=6.7222,P<0.01,OR=0.2000,95%CI:0.0371～0.7070),室内蚊密度高的比例病例组显著高于对照组(χ2=7.6923,P<0.01,OR=12.0000,95%CI:1.7755～512.9727),有蚊虫叮咬史的比例病例组显著高于对照组(χ2=7.6923,P<0.01,OR=12.0000,95%CI:1.7755～512.9727),有乙脑免疫史的比例病例组明显低于对照组(χ2=15.4286,P<0.01,OR=0.0500,95%CI:0.0012～0.3126)。多因素分析结果显示,使用灭蚊器蚊香、蚊虫叮咬史,乙脑疫苗免疫史等具有统计学意义。结论:室内卫生、室外环境卫生及乙脑疫苗免疫史是儿童乙脑发病的保护因素,使用灭蚊器蚊香、室内蚊密度、蚊虫叮咬史是儿童乙脑发病的危险因素。

Study on the Influencing Factors of Children Japanese Encephalitis in Case-control Study in Kaijiang County

Objective： To study the influencing factors of children Japanese encephalitis （JE） in Kaijiang county and to provide scientific bases for JE prevention and control tactics. Methods： Case-control was used to collect the information form 32 children JE cases and 32 controls. Information would include father and mother schooling, family economy income, indoor living health and outdoor environmental sanitation, prevent mosquito and destroy mosquito, indoor mosquitoes density, time with Mosquitoes bite, keep Pig rate, JE prevention and control knowledge knowing rate, time of JE vaccine immunization. Results： Single-factor analysis： the case group good of the indoor living health than the control group with statistical significance （χ^2=9. 3889,P〈0. 01,OR=0. 1250,95%CI：0. 0139～0. 5317）, the case group good of the outdoor environmental sanitation than the control group with statistical significance （ χ^2 = 6. 7222, P〈0. 01, OR = 0. 2000, 95 %CI：0. 0371～0. 7070）, the case group the indoor mosquitoes density is higher than the control group with statistical significance（ χ^2= 7. 6923, P〈0.01, OR = 12. 0000,95 % CI： 1. 7755 ～ 512. 9727）, the case group were time of Mosquitoes bite is higher than the control group with statistical significance（χ^2= 7. 6923,P.0.01,OR= 12. 0000,95 % CI： 1. 7755-512. 9727）, the case group were immunized with J E vaccine is higher than the control group with statistical significance（χ^2= 15. 4286, P〈0. 01,0R=0. 0500,95%CI： 0. 0012～0. 3126）. Much-factor analysis, apply destroy mosquito machine and mosquito-repellent incense, time with Mosquitoes bite, immunized with JE vaccine, all have statistical significance. Conclusion： The indoor living health good and the outdoor environmental sanitation good and have immunized with JE vaccine is protect fac- tors of children JE, the indoor mosquitoes density higher, apply destroy mosquito machine and mosquito-repellent incense, have time with Mosquitoes bite is incidence factors of children