| 表面脱钙骨基质明胶诱导成骨修复颅骨大面积缺损的实验研究 |
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| 引用本文： | 李明善,马开明. 表面脱钙骨基质明胶诱导成骨修复颅骨大面积缺损的实验研究[J]. 河南大学学报(医学版), 2008, 27(1): 50-52 |
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| 作者姓名： | 李明善 马开明 |
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| 作者单位： | 河南大学,神经生物学研究所,河南,开封,475004;河南大学,神经生物学研究所,河南,开封,475004 |
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| 摘 要： | 目的:寻找替代自体骨移植修复颅骨大面积缺损的理想材料。方法:用表面脱钙骨基质明胶修复大鼠颅骨8 mm的圆形缺损,术后不同时间行x线、组织学检查。结果:表面脱钙骨基质明胶具有诱导成骨能力,保留骨的部分生物力学特性,但完全被新骨替代时间较长。结论:表面脱钙骨基质明胶是修复大面积颅骨缺损的理想材料。
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| 关 键 词： | 表面脱钙骨基质明胶 诱导成骨 颅骨 |
| 文章编号： | 1672-7606(2008)01-0050-03 |
| 修稿时间： | 2007-12-27 |
Experimental study on osteoinduction of surface decalcified bone matrix gelatin for repairing large skull defects |
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| LI Ming-shan,MA Kai-ming. Experimental study on osteoinduction of surface decalcified bone matrix gelatin for repairing large skull defects[J]. Journal of Henan University, 2008, 27(1): 50-52 |
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| Authors: | LI Ming-shan MA Kai-ming |
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| Affiliation: | LI Ming-shan,MA Kai-ming(Neurobiology Institute of Henan University,Kaifeng 475004,China) |
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| Abstract: | Objective: To search for the ideal substitutes for autograft in repairing large skull defects.Methods: An 8mm in diameter damage of the Rat′s skull was repaired by surface decalcified bone matrix gelatin(SDBMG),X-ray and histological examination were performed at different period after operation.Results: Surface decalcified bone matrix gelatin has the ability of osteoinduction,and portional characteristic of biomechanical strength,but it needed longer time to be replaced completely by new bone.Conclusion: SDBMG is an ideal material for repairing large skull defects. |
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| Keywords: | Surface decalcified bone matrix gelatin Osteoinduction Skull |
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