| 力克肺疾与莫西沙星联合治疗耐多药肺结核近期疗效 |
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| 引用本文： | 洪梅,郑泽锋,吴捷,翁加豪. 力克肺疾与莫西沙星联合治疗耐多药肺结核近期疗效[J]. 热带医学杂志, 2009, 9(8) |
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| 作者姓名： | 洪梅 郑泽锋 吴捷 翁加豪 |
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| 作者单位： | 广东省汕头市第三人民医院,汕头,515073 |
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| 摘 要： | 目的评价力克肺疾与莫西沙星联合方案对耐多药肺结核(MDR-TB)的疗效。方法100例MDR-TB患者随机分为两组,每组50例。治疗组用莫西沙星0.4 g/d,力克肺疾1.0 g/d。对照组用左氧氟沙星0.4 g/d,丁胺卡那霉素0.6 g/d,疗程12个月,同时辅以其他抗结核药。结果第3个月末,治疗组痰菌转阴率为74%,明显优于对照组的43%,两组比较差异有统计学意义(P<0.05)。疗程结束时,治疗组痰菌转阴率为96%,明显优于对照组的70%,两组比较差异有统计学意义(P<0.05)。结论以力克肺疾与莫西沙星联合其他抗结核药物组成的化疗方案对MDR-TB疗效肯定,痰菌转阴速度快,值得继续临床探索。
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| 关 键 词： | 肺结核 耐多药 莫西沙星 力克肺疾 |
Curative Effect of Dipasic Combined with Moxifloxacin on Multi-drug Resistant Tubuculosis |
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| HONG Mei,ZHEN Ze-feng,WU Jie,WENG Jia-hao. Curative Effect of Dipasic Combined with Moxifloxacin on Multi-drug Resistant Tubuculosis[J]. Journal Of Tropical Medicine, 2009, 9(8) |
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| Authors: | HONG Mei ZHEN Ze-feng WU Jie WENG Jia-hao |
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| Affiliation: | The Third People's Hospital of Shantou City;Guangdong;Shantou 515073;China |
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| Abstract: | Objective To evaluate the curative effect of dispasic combined with moxifloxacin on multi-drug resistant tubuculosis.Method 100 patients are equally divided into two groups:Patients of therapeutic group treated with moxifloxacin 0.4 / d and another corresponding group treated with Levofloxacin 0.4 g / d,period of patient treatment combined with other assitant pneumonia drug for 12 months.Result By the end of 3rd month,negative ratio of therapeutic group reached 74%,superior to another group which reached 43... |
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| Keywords: | pneumonia tubuculosis multi-drug resistant moxifloxacin dispasic |
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