| 盐酸倍他洛尔片含量的紫外分光光度法测定 |
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| 引用本文： | 张红岭,吴春丽,王照川,周天洋,邵红,张振中.盐酸倍他洛尔片含量的紫外分光光度法测定[J].郑州大学学报(医学版),2007,42(3):574-576. |
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| 作者姓名： | 张红岭 吴春丽 王照川 周天洋 邵红 张振中 |
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| 作者单位： | 1. 郑州大学药学院,郑州,450001
2. 中南大学湘雅医学院,长沙,410078 |
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| 摘 要： | 目的:建立盐酸倍他洛尔片剂含量的紫外分光光度测定法.方法:采用紫外分光光度法,以水为空白对照,273 nm为测定波长,测定盐酸倍他洛尔的含量.结果:盐酸倍他洛尔质量浓度在50.02～300.04 mg/L范围内线性关系良好(r=0.999 9,n=5),平均加样回收率为99.36%.结论:该法操作简便、精密度好、结果可靠,适用于盐酸倍他洛尔片含量的快速测定.
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| 关 键 词： | 盐酸倍他洛尔片 紫外分光光度法 分析 |
| 收稿时间： | 2006-08-17 |
| 修稿时间： | 2006-08-17 |
Determination of Betaxolol hydrochloride by ultraviolet spectrophotometry |
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| ZHANG Hongling,WU Chunli,WANG Zhaochuan,ZHOU Tianyang,SHAO Hong,ZHANG Zhenzhong.Determination of Betaxolol hydrochloride by ultraviolet spectrophotometry[J].Journal of Zhengzhou University: Med Sci,2007,42(3):574-576. |
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| Authors: | ZHANG Hongling WU Chunli WANG Zhaochuan ZHOU Tianyang SHAO Hong ZHANG Zhenzhong |
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| Institution: | 1 College of Pharmacy, Zhengzhou University, Zhengzhou 450001 ;2 Xiangya Medical College, Zhongnan University, Changsha 410078 |
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| Abstract: | Aim: To establish ultraviolet spectrophotometry method for the determination of Betaxolol hydrochloride. Methods:The contents of Betaxolol hydrochloride were determined at 273 nm with water as the blank control by ultraviolet spectrophotometry. Results: The calibration curve of Betaxolol hydrochloride was linear when its concentration range was from 50.02 to 300.04 mg/L(r=0.999 9,n=5), and the average recovery was 99.36%. Conclusion: The method is convenient in operation,precise,reliable in results,and can be used as rapid determination for Betaxolol hydrochloride in tablets. |
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| Keywords: | Betaxolol hydrochloride tablet ultraviolet spectrophotometry analysis |
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