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P21WAFI和PCNA在鼻咽癌中的表达
引用本文:邹桂兰,游梨汀,刘勇. P21WAFI和PCNA在鼻咽癌中的表达[J]. 实用医技杂志, 2000, 7(6): 409-410
作者姓名:邹桂兰  游梨汀  刘勇
作者单位:江西省崇仁县人民医院 344200(邹桂兰,游梨汀),江西省人民医院 330006(刘勇)
摘    要:目的:探讨鼻咽癌中P21WAFI和PCNA表达异常的意义。方法:免疫组织化学(S—P)方法和显微摄像计算机图像分析技术。结果:55例鼻咽癌中P21WAFI阳性32例(58.2%),PI=62.32±13.647。结论:提示P21WAFI的低表达和PCNA的过表达在鼻咽癌细胞增殖和转移过程中起重要作用。

关 键 词:鼻咽癌  基因  增殖细胞核抗原  免疫组织化学

The expressions of P21/WAFI and PCNA in the nasopharyngeal cancer.
ThePeople's Hospital of Chongren city Zou CuiLan etal. .. The expressions of P21/WAFI and PCNA in the nasopharyngeal cancer.[J]. Journal of Practical Medical Techniques, 2000, 7(6): 409-410
Authors:ThePeople's Hospital of Chongren city Zou CuiLan etal. .
Affiliation:ThePeople's Hospital of Chongren city Zou CuiLan etal. 344200.
Abstract:Objective To study the meaning of expressions of p21/WAFI and PCNA in the nasopharyngeal cancer. Methods By using S-P immunohistochemical methods and the picture analyzing system in computer. Result The positive expressions for p21/WAF were 58. 2% and PI = 62. 32 13. 647 in the nasopharyngeal cancer. Conclustons the results show that p21/WAFI low expression and PCNA overexpression plays important role in cell proliferation andmatastasia of nasopharyngeal cancer.
Keywords:nasopharygeal cancer gene PCNA immunohistochemistry
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