| 雌二醇对兔离体血管条收缩及钙流动的影响 |
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| 引用本文： | 艾努尔·肖克来提.雌二醇对兔离体血管条收缩及钙流动的影响[J].实用医技杂志,2000(6). |
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| 作者姓名： | 艾努尔·肖克来提 |
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| 作者单位： | 新疆医科大学 830000 |
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| 摘 要： | 用离体兔胸主动脉条标本观察雌二醇对NE、KCL和CaCl_2引起血管收缩的量—效曲线的影响,发现大剂量Est使NE、KCL和CaCl_2的量—效曲线非平行右移,最大反应均轻度压低IC_(50),分别为250umol.L~(-1)和220umol.L~(-1);”提示Est的扩张血管作用,可能与抑制血管平滑肌膜Ca~(++)内流内关。
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| 关 键 词： | 雌二醇 主动脉 NE、KCL、CaCl_2、Ca~(++)通道 |
Effects of estradiol on contraction and calcium flux of rabbit vascutarstrips in vitro. |
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| Physiololgy teaching Reserch Room of Xinjiang Vygur Autonomous Reginal Medical college Ainur Maynur,..Effects of estradiol on contraction and calcium flux of rabbit vascutarstrips in vitro.[J].Journal of Practical Medical Techniques,2000(6). |
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| Authors: | Physiololgy teaching Reserch Room of Xinjiang Vygur Autonomous Reginal Medical college Ainur Maynur |
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| Institution: | Physiololgy teaching Reserch Room of Xinjiang Vygur Autonomous Reginal Medical college Ainur Maynur,830000. |
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| Abstract: | The effects of estradiol on the does -response curves of NE,KCLandCaCl2 were studied on the isolated rabbit aortic strip the test results havebeen shown that Est shifetd the does response curves of NE, KCLand CaCl2 tothe right unparallely with these IC50 of 250umol/L, 200umol/L and 220umol/L. These results suggest that the relaxing dffect of Est on rabbit bloodvessels may be relevant to the rabbit blood vessels may be relevant to theinhibition of Ca influx into vascular smooth muscle. |
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| Keywords: | 17 -B-estradiol Aorta Calciumchannel NE KCL CaCl2 |
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