保留BMP的微脱矿骨条在脊柱融合术中的应用研究 |
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引用本文: | 张爱明 李 青 蔡 林 袁元杏 梁道臣 梅 治 赵成毅. 保留BMP的微脱矿骨条在脊柱融合术中的应用研究[J]. 生物骨科材料与临床研究, 2011, 8(5): 23-25. DOI: 10.3969/j.issn.1672-5972.2011.05.007 |
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作者姓名: | 张爱明 李 青 蔡 林 袁元杏 梁道臣 梅 治 赵成毅 |
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作者单位: | 1. 中山市人民医院脊柱外科,广东,中山,528403 2. 武汉大学中南医院骨科,湖北,武汉,430071 |
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摘 要: | 目的探讨保留BMP的微脱矿骨条在脊柱融合术中的临床疗效。方法自2005年6月~2010年12月应用保留BMP的微脱矿骨条行脊柱融合术26例﹙实验组﹚,其中颈椎8例,胸腰椎18例,术后对所有患者行切口愈合情况、异物反应及脊柱融合情况进行观察,对照组为同期应用普通同种异体骨条行脊柱后路融合术26例。结果实验组与对照组伤口均一期愈合,未发生感染。颈椎实验组、对照组均现脊柱融合;胸腰椎实验组坚强融合16例,可能融合2例,对照组坚强融合13例,可能融合5例。随访6~24月,平均15.2月,内固定系统无松动及断钉断棒。结论保留BMP的微脱矿骨条应用在脊柱融合术中,脊柱融合可,无排异、感染等并发症,临床疗效满意。
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关 键 词: | 脊柱 融合 微脱矿 BMP |
Clinical research of demineralized bone with BMP in spinal fusion |
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Affiliation: | Zhang Aiming, Li Qing, Cai Lin, et a 1.Department of Spinal surgery, Zhongshan People s Hospitol, Zhongshan Guangdong, 528403, China 12 Department of orthopedics, Zhongnan Hospital of Wuhan University,, Wuhan Hubei,430071, China. |
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Abstract: | Objective To study the efficacy of spinal fusion by demineralized bone with BMP. Methods From Jun 2005 to Dec 2010, 26 patients underwent spinal fusion ~ 8 cases of cervical, 18 cases of thoracolumbar )by demineralized bone with BMP while the control group with allograft bone. The clinical efficacy were evaluated from primary incision healing 、 fusion status. Result All skin incision healed primarily with no infection, the 8 cases of cervical obtained satisfying fus- ion ; the 18 cases of thoracolumbar. In experimentmal group 16 cases with solid fusion and 2 with uncertain fusion while 13 with solid fusion and 5with uncertain fusion in control group. During 6 to 24 months ~ mean 15.2 months ) follow-up period, no screw looseness and no broken screw occurred. Conclusion Spinal fusion by demineralized bone with BMP has an advantage of satisfying fusion and no infection which can take good clinic effect |
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Keywords: | Spine Fusion Demineralization BMP |
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