| 干细胞移植治疗心肌梗死 |
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| 引用本文： | 黎健. 干细胞移植治疗心肌梗死[J]. 中国动脉硬化杂志, 2005, 13(1): 1-4 |
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| 作者姓名： | 黎健 |
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| 作者单位： | 卫生部北京老年医学研究所,北京市,100730 |
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| 基金项目： | 国家自然科学基金 ( 3 0 3 70 5 82 )资助 |
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| 摘 要： | 近年来,干细胞包括骨骼肌成肌细胞、胚胎干细胞和骨髓干细胞已被应用于心肌再生.心肌梗死动物模型的实验研究表明,干细胞移植改善了梗死心肌的功能,但其作用机制尚不十分清楚.本文对干细胞移植治疗心肌梗死研究中取得的成就、目前的研究焦点和有待解决的问题以及临床应用的潜力做一个总的评述.
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| 关 键 词： | 病理学与病理生理学 干细胞 心肌梗死／治疗 细胞移植 |
| 文章编号： | 1007-3949(2005)13-01-0001-04 |
| 收稿时间： | 2005-01-18 |
| 修稿时间： | 2005-01-18 |
Transplantation of Stem Cells for the Treatment of Myocardial Infarction |
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| LI Jian. Transplantation of Stem Cells for the Treatment of Myocardial Infarction[J]. Chinese Journal of Arteriosclerosis, 2005, 13(1): 1-4 |
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| Authors: | LI Jian |
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| Affiliation: | Beijing Institute of Geriatrics, Ministry of Health, Beijing 100730, China |
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| Abstract: | During the last few years stem cells including skeletal myoblasts, embryonic stem cells and bone marrow-derived stem cells have been proposed for myocardial regeneration. The experimental studies in animal models of infarction have documented the efficacy of stem cell transplantation in improving function of infarcted myocardium although the mechanisms involved in this improvement are not elucidated. This comment will try to present an overview of encouraging data, focus and questions on stem cells for treatment of myocardial infarction. I also provide my insight into the clinical potential for stem cell implantation. |
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| Keywords: | Stem Cells Myocardial Infarction Cell Transplantation |
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