大肠腺瘤危险因素的病例对照研究

目的:研究广东省惠州地区大肠腺瘤的相关危险因素,以便能更好地监测和预防本地区的大肠癌。方法:采用基于结肠镜检查为基础的病例-对照研究,应用Logistic回归对大肠腺瘤相关变量进行单因素和多因素分析。把可能的相关因素先行单因素分析,发现某些有意义的因素后,纳入Logistic回归模型进行多因素分析。结果:有统计学意义的危险因素有年龄≥45岁、排血便或黏液血便、排稀水便、轻度体力活动、吸烟≥11～20支/d,未发现有意义的相关保护因素。结论:惠州地区大肠腺瘤的发病与年龄、体力活动、吸烟、排便性状有关。

A case- control study on the risk factors for colorectal adenomas

Objective To investigate the risk factors of colorectal adenomas in Huizhou area, Guangdong province and provide better monitoring and prevention for local colorectal cancer. Methods With a colonoscopy- based case- control study, Logistic regression model was used for univariate and multivariate analysis of colorectal adenomas. Forward univariate analysis was used to select significant factors, and then the data was brought into multivariate analysis of Logistic regression model. Results The risk factors in...