| 机械通气对重症监护病房患者睡眠影响的研究 |
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| 引用本文： | 施巍,姜虹,朱也森. 机械通气对重症监护病房患者睡眠影响的研究[J]. 上海医学, 2010, 33(2) |
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| 作者姓名： | 施巍 姜虹 朱也森 |
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| 作者单位： | 上海交通大学医学院附属第九人民医院麻醉科,200011 |
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| 摘 要： | 目的 探讨机械通气对重症监护病房(ICU)患者睡眠时间及睡眠分裂的影响.方法 选择ICU的术后患者50例,分为5组,每组10例.对照组(C组),自主呼吸无镇静;T_0组,气管插管自主呼吸,无镇静;T_s组,低剂量镇静下气管插管自主呼吸;T_(m1)组,低剂量镇静下气管插管机械通气;T_(m2)组,高剂量镇静下气管插管机械通气.镇静药物为咪达唑仑.应用多导睡眠仪监测患者自22:00至次日6:00的睡眠时间及睡眠分裂.结果 与C组比较,T_0、T_(m1)T_(m2)组的睡眠时间显著缩短,T_0和T_(m1)组的睡眠效率显著降低(P值分别<0.01、0.05).T_0组患者的睡眠时间为(171±85)min,较T_s组的(296±87)min显著缩短(P<0.01);睡眠唤醒、觉醒次数为(35±15)次/h,较T_s组的(13±5)次/h显著增多(P<0.01).而T_s组的睡眠时间较T_(m1)组的(165±68)min显著延长(P<0.01),与T_(m2)组(245±86)min的差异无统计学意义(P>0.05);睡眠唤醒、觉醒次数较T_(m1)组的(31±14)次/h显著减少(P<0.01).结论 机械通气患者的睡眠时间缩短.睡眠分裂加重,高剂量镇静可延长其睡眠时间,减少睡眠分裂.
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| 关 键 词： | 重症监护病房 机械通气 睡眠障碍 镇静 |
Effects of mechanical ventilation on sleep of patients in the intensive care unit |
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| SHI Wei,JIANG Hong,ZHU Yesen. Effects of mechanical ventilation on sleep of patients in the intensive care unit[J]. Shanghai Medical Journal, 2010, 33(2) |
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| Authors: | SHI Wei JIANG Hong ZHU Yesen |
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| Affiliation: | SHI Wei,JIANG Hong,ZHU Yesen.Department of Anesthesia,Shanghai Ninth People's Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200011,China |
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| Abstract: | Objective To study the effects of mechanical ventilation on sleep duration and sleep fragmentation of patients in the intensive care unit.Methods Fifty patients in the intensive care unit(ICU) were assigned to a control group(spontaneous breathing without tracheal intubation) and experimental group(spontaneous breathing or mechanical ventilation under tracheal intubation).The experimental groups were sedated with different doses of midazolam and were subsequently divided into T0 group(spontaneous breathing ... |
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| Keywords: | Intensive care unit Mechanical ventilation Sleep disorders Sedation |
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