Renal dysfunction and transcatheter aortic valve implantation outcomes |
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Authors: | Marco Barbanti Giuseppe Gargiulo Corrado Tamburino |
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Affiliation: | 1. Division of Cardiology, Ferrarotto Hospital, University of Catania, Catania, Italy;2. Division of Cardiology - Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy;3. Excellence Through Newest Advances (ETNA) Foundation, Catania, Italy |
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Abstract: | Introduction: Transcatheter aortic valve implantation (TAVI) underwent progressive improvements until it became the default therapy for inoperable patients, and a recommended therapy in high-risk operable patients with symptomatic severe aortic stenosis. Recent evidence will further support TAVI as treatment for a growing number of patients. Areas covered: This review will discuss on the current knowledge about the role of both pre-procedural chronic kidney disease (CKD) and post-procedural acute kidney injury (AKI) in adult patients with severe aortic stenosis undergoing TAVI. Expert commentary: Pre-procedural CKD is one of the most frequent comorbidities of TAVI patients and has been found to significantly worsen patients’ prognosis at short and long-term follow-up. Similarly, post-procedural AKI is a frequent and relevant complication associated with increased mortality. The risk stratification of the patient, the prevention of complications and the appropriate post-procedural management are the main focus of the future research aimed at further improving clinical outcomes of TAVI patients. |
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Keywords: | TAVI renal dysfunction chronic kidney disease acute kidney injury mortality |
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