抗肿瘤治疗所致心脏毒性的研究进展

恶性肿瘤是目前社会的主要死亡原因之一，随着抗肿瘤治疗方法的不断进步，癌症患者的生存率显著提高。由于癌症患者的生存期延长，癌症治疗所引起的相关心血管不良事件的发生率明显升高，引起心脏病学家越来越多的关注。抗肿瘤治疗引起的主要心脏毒性包括左室收缩功能障碍和心功能不全，此外还可能产生其他心脏毒性，如高血压、心包疾病、心律失常、血栓栓塞及房颤等。心脏病学家已制定治疗策略，优化检测手段，预防和监测癌症治疗过程中的心脏毒性，以提高患者生活质量。本文主要对抗肿瘤治疗所致常见心脏毒性进行综述。

Research progress of cardiotoxicity induced by anti-tumor treatment

Malignant tumor is one of the main causes of death in society at present.The survival rate of cancer patients is significantly improved by modern anti-tumor treatment.For the long living of cancer patients,the incidence of cardiovascular adverse events is significant increased with the development of anti-tumor treatment,and cardiologists pay more attention on it.The main cardiac toxicity induced by anti-tumor therapy includs left ventricular systolic dysfunction,heart failure,hypertension,pericardial disease,arrhythmia,thrombosis,atrial fibrillation and etc.Cardiologists have developed therapeutic strategies and optimization methods to prevent and detect cardiac toxicity in the process of anti-tumor treatment in order to improve the living quality of cancer patients.The common cardiac toxicity caused by anti-tumor treatment will be discussed in this review.