正常人多焦视网膜电图一、二阶函数核反应特征分析

目的:比较正常人多焦视网膜电图(multifocalelectroretinogram,mfERG)一、二阶函数核的波形及视网膜分布特点。方法:使用VERISScienceTM4.0系统,采用对比度为96%的103个六边形刺激模式,记录了17只正常人眼mfERG。结果:与一阶函数核相比较,mfERG二阶函数核波形较复杂、子波较多。其中一片反应一般有三个正向及负向波,而二片反应有四个正向及负向波。除潜伏期外,二阶函数核与一阶函数核振幅反应的视网膜分布特征基本一致,以中心凹处振幅密度反应最大,随离心度加大振幅逐渐降低;上方视网膜反应大于下方视网膜,颞侧视网膜反应大于鼻侧视网膜。但总能量明显小于一阶函数核。结论:正常人mfERG二阶函数核的视网膜分布特点与一阶函数核基本一致,二阶函数核对于某些疾病的诊断是否具有特异性,有待于进一步研究。

Comparative Analysis of First and Second Order Kernels of Multifocal Retinogram in Normal Subjects

Purpose:To compare the features of waveform and retinal distribution between first order kernel (FOK) and second order kernel (SOK) of multifocal electro retinogram (mfERG) in normal subjects. Methods:The mfERG were recorded in 17 normal eyes. The recordings were finished by the VERIS ScienceTM 4.0 system, with the condition of 96% contrast and 103 hexagons stimulating pattern. Results:Compared with the FOK, the waveform of SOK was complex with more wavelets. Generally, there were 3 positive and 3 negative waves in the first slice of SOK, and 4 positive and 4 negative in the second slice of SOK. Except the latencies, the retinal distributions of amplitude responses of FOK and SOK were almost the same as the following. The amplitude densities from central hexagon were the highest, and gradually decreased as the acentric degree increased. The amplitudes were larger in upper and temporal retina than those of lower and nasal retina. But the total energy of it was much smaller than that of FOK. Conclusions:The features of retinal distribution of SOK were almost the same as FOK in normal people. It needs further research on whether it has the specificity for some kinds of fundus diseases or not.