Reduction in pulmonary and hepatic respiratory cytochrome contents by fly ash inhalation in rats |
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| Authors: | S S Chauhan S R Tyagi R K Kapoor U K Misra |
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| Affiliation: | Department of Biochemistry, V.P. Chest Institute, University of Delhi, India. |
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| Abstract: | Exposure of rats to fly ash for 15 days, 6 hours daily, inhibited pulmonary and hepatic NADH-oxidase activity. The content of cytochrome b and cytochromes a + a3 was significantly lower in the lungs of the fly-ash-exposed group. However, in liver, fly ash exposure reduced the cytochrome a + a3 level without affecting the cytochrome b content, indicating a tissue-specific effect. Mitochondrial protein content in both organs was the same in both groups. |
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