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Langerhans cell histiocytosis in the mandible: Computed tomography and magnetic resonance imaging |
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| Authors: | Takashi Kaneda D.D.S. Ph.D. Manabu Minami M.D. Mitsuaki Yamashiro D.D.S. Yoshiaki Akimoto D.D.S. Ph.D. Hiroyuki Okada D.D.S. Ph.D. Hirotsugu Yamamoto D.D.S. Ph.D. Hiromi Suzuki D.D.S. Ph.D. Yasuhito Sasaki M.D. Ph.D. |
| Affiliation: | (1) Department of Radiology, Nihon University School of Dentistry at Matsudo, 2-870-1, Sakaecho-Nishi, 271 Matsudo, Chiba, Japan;(2) Department of Oral Surgery, Nihon University School of Dentistry at Matsudo, 2-870-1, Sakaecho-Nishi, 271 Matsudo, China, Japan;(3) Department of Pathology, Nihon University School of Dentistry at Matsudo, 2-870-1, Sakaecho-Nishi, 271 Matsudo, Chiba, Japan;(4) Department of Radiology, University of Tokyo Hospital, Tokyo, Japan |
| Abstract: | Langerhans cell histiocytosis in the mandible is a rare disease. The clinical and advanced imaging features of Langerhans cell histiocytosis in an 18-year-old male are presented. CT images showed an diffuse, ill-defined, expansile lesion of heterogeneous density extending from the anterior mandibular area to the right molar area. CT was particularly helpful in confirming a cortical invasion. T1-weighted gradient echo MR images revealed a heterogeneously low-to high-signal intensity lesion in the right side of the mandible. T2-weighted spin echo MR images showed a heterogeneously iso-to high-signal intensity area with low-intensity areas. Multidirectional MR images revealed the extent of the lesion in the mandibular bone marrow more clearly than CT. |
| Keywords: | Langerhans cell histiocytosis Mandible Magnetic resonance imaging X-ray computed tomography |
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