2001年～2004年广州市35家医院头孢菌素类抗生素利用分析

目的评价广州市部分医院头孢菌素类抗生素的应用状况及趋势。方法对2001年~2004年广州市35家医院头孢菌素类抗生素的应用品种、用药金额、用药频度(DDDs)等进行统计、分析。结果4年中,头孢菌素类抗生素的应用品种、用药金额、DDDs均逐年增加,总的用药金额和DDDs年平均增长率分别为13.18%和10.41%;第3代头孢菌素类抗生素用药金额最高,增长速度最快;口服用、注射用头孢菌素类抗生素品种均逐年增加,二者用药金额和DDDs的年平均增长率分别为7.63%、14.29%和9.41%、12.82%。结论为延缓细菌耐药性的产生,建议进一步规范化管理头孢菌素类抗生素的应用。

Analysis of Cephalosporins Antibiotics Used in 35 Hospitals of Guangzhou during 2001～2004

OBJECTIVE:To evaluate the utilization status of cephalosporins antibiotics and the tendency of which in some hospitals of Guangzhou city.METHODS:The cephalosporins antibiotics used in35hospitals of Guangzhou city in2001～2004were statistically analyzed in respect to the varieties,drug consumption sum and DDDs etc.RESULTS:During the4years,the varieties,consumption sum and DDDs of cephalosporins antibiotics increased year by year with total drug consumption sum and DDDs increased by13.18%and10.41%,respectively.The third generation cephalosporins antibiotics dominated the first place in terms of consumption sum,which had a fastest increase.The varieties of both oral cephalosporins antibiotics and cephalosporins antibiotics for injection increased with mean annual rates of increase of consumption sum and DDDs of oral cephalosporins antibiotics at7.63%and14.29%,respectively and9.41%and12.82%,respectively for cephalosporins antibi-otics for injection.CONCLUSION:To retard bacterial drug resistance,it is suggested that the utilization of cephalosporins antibiotics should be further normalized.