大肠癌腹腔CEA测定的临床意义

目的：为了探讨如何早期发现腹腔内隐匿性播散。方法：应用放射免疫法检测60例大肠癌的腹腔CEA与血清CEA值，CEA临界值定为15ng/ml。结果：大肠癌腹膜播散，浸润浆膜、未侵入浆膜，腹腔CEA阳性率分别为81．8%、54．5%、22．2%。三者差异显著（P＜0．01）。CEA阳性组2年生存率（29．1%）显著低于阴性组（88．9%）（P＜0．01）。结论：腹膜CEA检测比血清CEA检测更准确敏感，是判断腹腔内播散和预后的一种好方法。

Detection of CEA in Peritoneal Irrigation Fluid in Colorectal Cancer Patients

Objective: To evaluate how to detect invisible peritoneal dissemination. Methods: CEA levels in peritoneal irrigation fluid and in blood were detected by radioimmunology in co colorectal cancer Patients. Results: The results showed that the CEA positive rates in patients with visible peritoneal dissemination,serosal invasion and non - invaded peritoneum were 81. 8 %, 54. 5 %, 22. 2%, respectively. The 2 - year survival rate of CEA positive patients (29. 1% ) was markedly lower than that of the negative group (88. 9% ). Conclusion: The detection of CEA is more accurate and sensitive in peritoneal irrigation fluid than in the bind, and it is a good means for judging invisible peritoneal dissemination and prognosis evaluation.