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替米沙坦治疗原发性高血压逆转左心室肥厚
引用本文:王万成,王留义.替米沙坦治疗原发性高血压逆转左心室肥厚[J].医药论坛杂志,2006,27(17):13-14.
作者姓名:王万成  王留义
作者单位:郑州大学第五附属医院,郑州市,450052;河南省人民医院,郑州市,450003
摘    要:目的观察替米沙坦治疗原发性高血压逆转左心室肥厚的作用。方法选择66例原发性高血压且合并左心室肥厚的患者,采用自身对照的方法,在给予替米沙坦治疗前后测收缩压(SBP)、舒张压(DBP)、心率(HR)、左心室舒张末期室间隔厚度(IVST)、左心室后壁厚度(LVPWT)、左心室舒张末期内径(LVDd)、左心室重量指数(LVM I)。结果治疗24周后,SBP、DBP较治疗前明显下降(P<0.05)。IVST、LVPWT、LVDd、LVM I明显低于治疗前(P<0.05)。结论替米沙坦不仅能控制高血压,而且能够逆转高血压引起的左心室肥厚、疗效、安全性及耐受性均好。

关 键 词:原发性高血压  左心室肥厚  替米沙坦
文章编号:1672-3422(2006)17-0013-02
收稿时间:06 6 2006 12:00AM
修稿时间:2006年6月6日

Clinical Study of Hypertension with Left Ventricular Hypertrophy Treated by Telmisartan
WANG Wancheng,WANG Liuyi.Clinical Study of Hypertension with Left Ventricular Hypertrophy Treated by Telmisartan[J].Journal of Medical Forum,2006,27(17):13-14.
Authors:WANG Wancheng  WANG Liuyi
Institution:The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
Abstract:Objective To observe the treatment results of hypertension with left ventricular hypertrophy treated by telmisartan.Methods 66 hypertension with left ventricular hypertrophy patients were treated by telmisartan.the same time SBP,DBP,HR,IVST,LVPWT,LVDd and LVWI were observed before and after treatment.Results After 24 weeks treatment,SBP and DBP were singificantly lower than those before treatment(P<0.05).IVST,LVPWT,LVDd and LVMI were also significantly lower than those before treatment(P<0.05). Conclusion telmisartan not only can luw hypertention but also can reverse left ventricular hypertrophy.Its security is as well as enduring.
Keywords:Hypertension  Left ventricular hypertrophy  Telmisartan
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