Effects of exercise training on left ventricular function in normal subjects: A longitudinal study by radionuclide angiography

Radionuclide angiocardiography provides accurate hemodynamic information during maximal exercise in erect subjects. Cardiac function was studied with this noninvasive technique in 12 male and 6 female college athletes before (BT) and after (AT) 6 months of swimming training. Measurements at rest and during maximal exercise of heart rate, left ventricular ejection fraction, end-diastolic volume, cardiac output and total body blood volume were determined from first pass and equilibrium precordial counting techniques. The results were as follows:

	Heart Rate (beats/ min)	Ejection Fraction (%)	End-Diastolic Volume (ml)	Cardiac Output (liters/ min)	Total Body Blood Volume (liter)
Rest
BT	$\text{74 ± 11}$	$\text{73 ± 6}$	$\text{133 ± 35}$	$\text{6.9 ± 1.1}$	$\text{8.7 ± 0.8}$
AT	$\text{61 ± 7}$	$\text{67 ± 7}$	$\text{167 ± 40}$	$\text{6.7 ± 1.0}$	$\text{11.4 ± 2.2}$
Exercise
BT	$\text{185 ± 10}$	$\text{87 ± 4}$	$\text{166 ± 34}$	$\text{25.5 ± 5.7}$	$\text{8.0 ± 0.9}$
AT	$\text{181 ± 14}$	$\text{86 ± 5}$	$\text{204 ± 39}$	$\text{32.0 ± 8.7}$	$\text{10.8 ± 2.3}$
Keywords:	Address for reprints: Stephen K. Rerych   MD   P.O. Box 3830   Duke University Medical Center   Durham   North Carolina 27710.
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