| 补肾中药对骨质疏松大鼠骨骼的影响 |
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| 引用本文： | 宋献文,石印玉,沈培芝,张英. 补肾中药对骨质疏松大鼠骨骼的影响[J]. 中国骨伤, 1997, 10(5): 13-14 |
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| 作者姓名： | 宋献文 石印玉 沈培芝 张英 |
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| 作者单位： | 上海铁道大学附属甘泉医院!200065(宋献文)，上海中医药大学附属曙光医院(石印玉)，上海中医药研究院骨伤科研究所(沈培芝，张英) |
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| 摘 要： | 本实验以股骨密度、抗弯强度和股骨骨小梁体积为指标，观察补肾中药对骨质疏松大鼠骨骼的影响。用卵巢切除的方法建立大鼠骨质疏松模型，然后对模型分别给乙烯雌酚或中药治疗3个月后发现，乙烯雌酚或中药治疗可以阻止股骨密度，抗弯强度和胫骨骨小梁体积的下降，但两种药物均不能使已经下降的股骨密度、抗弯强度和胫骨骨小梁体积升高。这一结果提示：补肾中药对骨质疏松大鼠有防治作用。
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| 关 键 词： | 骨质疏松 骨 中草药 大鼠 |
| 收稿时间： | 1996-06-06 |
Effect of Chinese Kidney-tonifying Drug on Bone of Osteoporotic Rat |
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| Song Xianwen,Shi Yinyu,Shen Peizhi. Effect of Chinese Kidney-tonifying Drug on Bone of Osteoporotic Rat[J]. China journal of orthopaedics and traumatology, 1997, 10(5): 13-14 |
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| Authors: | Song Xianwen Shi Yinyu Shen Peizhi |
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| Affiliation: | Song Xianwen, Shi Yinyu, Shen Peizhi, et al. |
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| Abstract: | The effect of Chinese kidney -tonifying drugs on bones of osteoporotic rats were investigated by detecting bone mineral density (BMD ), resistance bending strength (RBS) and bone trabecular volume (BTV). Femal rats were ovariectomized to build the model of osteoporosis, and then treated with Chinese drugs and stilbestrol respectively for 3 months. The results showed that both Chinese drugs and stilbestrol prevented the BMD, RBS and BTV from further declining in osteoporotic rats; but could not raise the BMD, RBS and BTV that had declined. The writers suggested that Chinese drugs with kidney - tonifying action might prevent and treat rats' osteoporosis. |
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| Keywords: | Osteoporosis Bone Chinese drug Rat |
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