| Effects of procainamide on 0morphological parameter of dense granule and a granule in blood platelet |
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| 作者姓名： | 林继红 单春文 杨素勤 刘连璞 顾为望 |
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| 作者单位： | Lin Jihong，Shan Chunwen，Yang Suqin，Liu Lianpu，Gu Weiwang )(Experimental Animal Center)(Department of Pharmacology)(Department of Electron Microscopy，First Military Medical University，Guangzhou，510515) |
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| 摘 要： | Wehaveaccomplishedanumberofresearchesforprocainamide(PA).ItwasdemonstratedthatPAinhibitedADP--.AA--.thromhln--.collagen--,PAF(platelet--activatingfactor).CaCI,--,A23187,andotherinducedplateletaggregationsignificantly,andinhibitedtheincreaseincytosolicfreeCaZ--andtheproductionofthromboxaneBZ(TXB,)andmalondialdehyde(MDA)inbloodplatelet.PAshiftedtheclonidine--inducedconcentration--dependentplateletaggregationcurvesofabsorbancetotherightinaparallelfashion,andalsoreducedplateletadhesion.a…
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Effects of procainamide on 0morphological parameter of dense granule and a granule in blood platelet |
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| Lin Jihong,Shan Chunwen,Yang Suqin,Liu Lianpu,Gu Weiwang.Effects of procainamide on 0morphological parameter of dense granule and a granule in blood platelet[J].Journal of Medical Colleges of PLA(China),1999(2). |
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| Authors: | Lin Jihong Shan Chunwen Yang Suqin Liu Lianpu Gu Weiwang |
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| Abstract: | |
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| Keywords: | procainamide arachidonic acid blood platelet electron microscopy stereology measllrement |
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