| 原发性肝癌组织和血清蛋白结合岩藻糖检测的初步报告 |
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| 引用本文： | 颜洁明 杨秀珍. 原发性肝癌组织和血清蛋白结合岩藻糖检测的初步报告[J]. 徐州医学院学报, 1994, 14(4): 320-322 |
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| 作者姓名： | 颜洁明 杨秀珍 |
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| 作者单位： | Laboratory of Digestion，Xuzhou Medical College，Xuzhou，Jiangsu 221002，China |
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| 摘 要： | 观察了５５例原发性肝癌，４０例慢性肝病，２５例肝良性占位血清蛋白结合岩藻糖的变化。４０例健康人作为对照。同时测定了１４例手术切除人肝癌组织、癌旁和远隔肝组织中蛋白结合岩藻糖的含量。结果发现：原发性肝癌血清蛋白结合岩藻糠明显地高于慢性肝病、肝良性占位和健康人（Ｐ均＜０．０１）。肝癌组织中蛋白结合岩藻糖高于癌旁和远隔肝组织（Ｐ＜０．０１）。提示血清蛋白结合岩藻糖可作为原发性肝癌辅助的诊断指标；有助于区别肝脏恶性占位。同时，还对其机制作了探讨。
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| 关 键 词： | 原性发 癌 蛋白结合岩藻糖 肝占位性病变 肝肿瘤 |
DETECTION OF FROTEIN BOUND FUCOSE IN TUMOROUS TISSUES AND SERA OF PATIENTS WITH PRIMARY HEPATOCELLULAR CARCINOMA |
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| Yan Jieming,Yang Xiuzhen, Fei Sujuan, Chen Jianqun. DETECTION OF FROTEIN BOUND FUCOSE IN TUMOROUS TISSUES AND SERA OF PATIENTS WITH PRIMARY HEPATOCELLULAR CARCINOMA[J]. Acta Academiae Medicinae Xuzhou, 1994, 14(4): 320-322 |
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| Authors: | Yan Jieming Yang Xiuzhen Fei Sujuan Chen Jianqun |
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| Abstract: | The protein bound fucose(PBF) was determined in the sera of 55 patients with primary hepatocellular carcinoma(PBC), 40 with chronic liver diseases,25 with benign liver space-occupying lesien and 40 normal controls,and in the tumorous and nontumorous liver tissues from 14 patients with pathologically proven PHC,Serum PBF in PRC was much higher than that in chronic liver diseases,benign liver space-occupying lesien and hormal controls(all P<0.01).PBF in tumorous liver tissue was higher than that in nontumorous(P<0.01). These results suggest that serum PBF may be taken as a tumor marker in PHC. It is of benefit to the differential diagnosis between benign and melignant space-occupying lesiens in the liver. |
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| Keywords: | primary hepatocellular carcinoma protein bound fucose differential diagnosis |
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