| 甲状腺,肾上腺和卵巢在电刺激室旁核加重大鼠应激性胃溃疡中的作用 |
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| 引用本文： | 张建福 郑芳. 甲状腺,肾上腺和卵巢在电刺激室旁核加重大鼠应激性胃溃疡中的作用[J]. 徐州医学院学报, 1994, 14(4): 306-308 |
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| 作者姓名： | 张建福 郑芳 |
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| 作者单位： | Department of Physiology，Xuzhou Medical College，Xuzhou，Jiangsu 221002，China |
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| 摘 要： | 用切除腺体的方法，观察了甲状腺、肾上腺、性腺在电刺激室旁核（ＰＶＮ）加重大鼠冷束缚应激性胃溃疡中的作用。结果表明：分别切除雌性大鼠的甲状腺、肾上腺、卵巢后，都能减轻电刺激室旁核（ＰＶＮ）加重的大鼠应激性胃溃疡，提示甲状腺、肾上腺、性腺都参与了下丘脑室旁核对应激性胃溃疡的调节。
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| 关 键 词： | 胃溃疡 应激性胃溃疡 室旁核 甲状腺 肾上腺 |
THE ROLES OF THYROID GLAND,ADRENAL GLANDS AND OVARIES IN THE AGGRAVATING EFFECT OF PARAVENTRICULAR NUCLEUS ON THE DEVELOPMENT OF STRESS GASTRIC ULCER IN RATS |
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| Zheng Fang, Zhang Jianfu. THE ROLES OF THYROID GLAND,ADRENAL GLANDS AND OVARIES IN THE AGGRAVATING EFFECT OF PARAVENTRICULAR NUCLEUS ON THE DEVELOPMENT OF STRESS GASTRIC ULCER IN RATS[J]. Acta Academiae Medicinae Xuzhou, 1994, 14(4): 306-308 |
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| Authors: | Zheng Fang Zhang Jianfu |
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| Abstract: | The neuroendocrine mechanism of the aggravating effect of paraventricular nucleus (PVN) stimulation on the development of stress gastric ulcer was investigated in rats. It was found that the aggravating effect was markedly reduced by thyroidectomy,unilateral adrenalectomy and bilateral ovariectomy, respectively. These results suggest that all of the hypothalamicpituitary-thyroid, adrenal and gonadal axes are involved in the aggravating effect 0f PVN stimulation 0n stress ulcer in rats. |
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| Keywords: | stress gastric ulcer paraventricular nucleus (PVN) thyroid gland adrenal gland gonad |
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