前列腺炎患者血清TPSA、FPSA及FPSA／TPSA比值与前列腺液WBC含量的比较分析

目的探讨前列腺炎患者血清总前列腺特异抗原（TPSA）、游离型前列腺特异性抗原（FPSA）及游离型前列腺特异性抗原／总前列腺特异抗原（FPSA／TPSA）比值与前列腺液门细胞（WBC）的相关性。方法通过化学发光法测定205例前列腺炎患者血清TPSA、FPSA、FPSA/PSA比值，再与前列腺液（EPS）镜检WBC含量作比较，分析不同EPS中WBC含量与血清TPSA、FPSA、FPSA／TPSA比值的关系，以及前列腺炎治疗前后血清TPSA、FPSA、FPSA／TPSA比值的变化，来确定两者的相关性，试验同时设对照组40例。结果前列腺炎较严重组（WBC＋＋＋～＋＋＋＋）血清FPSA、TPSA及FPSA/PSA比值与前列腺炎较轻组（WBC＋～＋＋）及正常对照组差异均有显著性（P〈0．05），前列腺炎治疗好转前后血清TPSA、FPSA、FPSA/PSA比值对比有显著性差异（P〈0．05）。结论前列腺炎可以导致血清TPSA、FPSA及FPSA-PSA升高，这种升高与EPS中WBC的含量呈正相关，血清TPSA、FPSA及FPSA-PSA升高也可以作为前列腺炎疗效判断的一项指标。

A comparison of serum TPSA,FPSA,and FPSA/TPSA with WBC content in expressed prostatic secretion in patients with prostatitis

Objoetive To investigate the correlation of serum TPSA,FPSA,and FPSA/TPSA with WBC content in expressed prostatic secretion(EPS)in patients with prostatitis.Methods Serum TPSA,FPSA.and FPSA/TPSA were detected with ECLIA technique in 205 patients and then were compared with the WBC content in EPS.The correlation of WBC in EPS with serum TPSA,FPSA,and FPSA/TPSA was analyzed.40 normal individuals were used as control.Results Serum TPSA,FPSA,and FPSA/TPSA differed significantly between the prostatitis group and the control group(P＜0.05) and between the group with higher WBC content and the group with lower WBC content(P＜0.05). and they also differed significantly after treatment.(P＜0.05). Conclusions Prostatitis may lead to an increase in serum TPSA,FPSA,and FPSA/TPSA and this change is related with the WBC content in EPS.The increased serum TPSA,FPSA,and FPSA/TPSA can be used as a index for of judging the efficacy of treatment.