| 可生物降解缓释技术在镇痛释药系统的应用 |
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| 引用本文： | 陆蕾,邹豪,高申. 可生物降解缓释技术在镇痛释药系统的应用[J]. 国际药学研究杂志, 2008, 35(5): 364-368 |
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| 作者姓名： | 陆蕾 邹豪 高申 |
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| 作者单位： | 第二军医大学药学院药剂学教研窒,上海,200433 |
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| 摘 要： | 作者查阅近10余年来镇痛药物可生物降解缓释给药系统在疼痛治疗应用中的文献，从常用于镇痛释药系统的可生物降解聚合物、可生物降解材料制备的新型镇痛释药系统、聚合物载体结构特征分析、用于评价镇痛释药系统的动物模型、镇痛释药系统的临床研究情况对该系统的研究进展进行归纳和总结，并对已上市的长效镇痛释药系统进行了介绍。
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| 关 键 词： | 镇痛药物； 生物降解聚合物； 镇痛释药系统 |
| 收稿时间： | 2008-03-25 |
Application of biodegradable sustained-release techniques in analgesic drug delivery system |
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| LU Lei,ZOU Hao,GAO Shen. Application of biodegradable sustained-release techniques in analgesic drug delivery system[J]. Foreign Medical Sciences(Section of Pharmarcy), 2008, 35(5): 364-368 |
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| Authors: | LU Lei ZOU Hao GAO Shen |
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| Affiliation: | （Department of Pharmaceutical Science, School of Pharmacy, the Second Military Medical University, Shanghai 200433, China） |
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| Abstract: | The application of biodegradable sustained-release analgesic drug delivery systems in pain management is reviewed in this article. The biodegradable polymers, forms of polymeric delivery systems, analysis of carrier structural features, animal models and clinical trials of novel biodegradable analgesic drug delivery systems are all-round introduced. Commercial available sustained/controlled-release products in pain management are also mentioned. |
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| Keywords: | analgesic drugs biodegradable polymers analgesic drug delivery systems |
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