消化不良病人胃窦胃体内镜表现及病理对比研究

目的研究功能性消化不良病人胃窦与胃体的内镜表现及病理检查的区别。方法2003-03~05对北京友谊医院门诊接受胃镜检查的132例有上消化道症状的病人,根据红斑、糜烂、出血和萎缩4种表现进行内镜评价,按胃黏膜慢性炎症、活动性、萎缩、肠化生、幽门螺旋杆菌和异型增生进行病理评价。分析胃窦与胃体内镜表现及病理的区别。结果胃窦与胃体相比,内镜下红斑和糜烂病变较为多发,P值均<0.01;病理诊断萎缩和慢性炎症,胃窦与胃体之间差异也很显著,P值分别为<0.001和<0.025。结论功能性消化不良病人胃窦与胃体在内镜和病理上存在差异,内镜下红斑和糜烂,以及病理萎缩和慢性炎症,在胃窦比胃体更常见。

The comparison of endoscopic and histological findings between antrum and corpus in functional dyspeptic patients

Objective To compare the differences between antrum and corpus in endoscopic and histological diagnosis in non-ulcer dyspeptic patients.Methods 132 cases from out-patient department who had been ordered to undergo gastroendoscopy for dyspepsia were enrolled in the study.After endoscopy,different signs including redness,erosion,intramural bleeding and rugal atrophy were described.Histological diagnosis was defined according to the classification of chronic inflammation,polymorphonuclear neutrophil activity,glandular atrophy,intestinal metaplasia,helicobacter pylori and dysplasia.The differences between antrum and corpus in endoscopic and histological diagnosis were analyzed.Results Redness and erosion under endoscopy,glandular atrophy and chronic inflammation in histological diagnosis were found more frequently in antrum than in corpus.P values were less than 0.001,0.01,0.001 and equaled to 0.025 respectively.Conclusion In functional dyspeptic patients,there are differences in the endoscopic and histological findings between antrum and corpus.Redness and erosion in endoscopic diagnosis,glandular atrophy and chronic inflammation in histological diagnosis are more common in antrum when compared with that in corpus.