Preoperative Transcatheter Arterial Chemoembolization and Prognosis of Patients with Hepatocellular Carcinomas: Retrospective Analysis of 120 Cases |
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| Authors: | Cai-De Lu Shu-You Peng Xien-Chuan Jiang Yukio Chiba Nobuhiko Tanigawa |
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| Institution: | (1) Department of Surgery, The Second Affiliated Hospital of Zhejiang University Medical School, 68 Jie Fang Road, Hangzhou 310009, Republic of China, CN;(2) Second Department of Surgery, Fukui Medical College, Matsuoka-Cho, Fukui 910-11, Japan, JP;(3) Department of General and Gastroenterological Surgery, Osaka Medical College, 2-7 Daigaku-Machi, Takatsuki City Osaka 569-8686, Japan, JP |
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| Abstract: | 1 (n= 24) and B1 (n= 57), and those with tumors > 8 cm were assigned to groups A2 (n= 20) and B2 (n= 19), respectively. Although no significant differences in survival between groups A1 and B1 were found, group A2 presented superior 1-, 2-, and 3-year tumor-free survival rates of 80%, 55%, and 32% and 1-, 3-, and 5-year cumulative survival
rates of 90%, 53%, and 42%. These figures are in comparison with the tumor-free survival rates of 50%, 22%, and 11% (p= 0.06), and the cumulative survival rates of 72%, 33%, and 11% (p= 0.01) during the same periods for group B2, respectively. The Cox regression model revealed that for patients with tumors > 8 cm, the relative risk of preoperative
TAE for overall survival was 0.38 (p= 0.017), indicating that preoperative TAE might benefit patients with tumors > 8 cm but not those with tumors 2 to 8 cm. |
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