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| 幽门螺杆菌特异性抗体体外杀菌机理的探讨 | |
| 引用本文： | 刘宝文,王利青,王薇,孙晓丽,王沛,赵亚朴,徐华州,钟立强. 幽门螺杆菌特异性抗体体外杀菌机理的探讨[J]. 临床军医杂志, 2002, 30(1): 49-50 |
| 作者姓名： | 刘宝文 王利青 王薇 孙晓丽 王沛 赵亚朴 徐华州 钟立强 |
| 作者单位： | 1. 解放军白求恩军医学院,河北,石家庄,050081 2. 石家庄市防疫站,河北,石家庄,050081 3. 河北省中医学院,河北,石家庄,050081 |
| 摘 要： | 目的 探讨幽门螺杆菌 (HP)特异性抗体对胃、十二指肠疾病的免疫治疗机理。方法 用HP菌及其特异性抗体、胃液、补体进行不同的试验组合观察体外杀菌作用。结果 在pH <4的环境下 ,HP与其特异性抗体结合 ,然后激活胃液中的补体 ,最终导致溶菌使HP被杀灭。实验体系中缺少抗体或补体均不会将HP杀灭。结论 口服特异性HP抗体治疗HP感染有着美好的前景 |
| 关 键 词： | 幽门螺杆菌 幽门螺杆菌特异性抗体 体外抗菌 |
| 文章编号： | 1671-3826(2002)01-0049-02 |
| 修稿时间： | 2001-06-14 |
Study on the Mechanism of HP-specific Antibody Against Bacterium |
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| LIU Bao wen,WANG Li qing,WANG Wei,SUN Xiao li,WANG Pei,ZHAO Ya pu,XU Hua zhou,ZHONG Li qiang. Study on the Mechanism of HP-specific Antibody Against Bacterium[J]. Clinical Journal of Medical Officer, 2002, 30(1): 49-50 | |
| Authors: | LIU Bao wen WANG Li qing WANG Wei SUN Xiao li WANG Pei ZHAO Ya pu XU Hua zhou ZHONG Li qiang |
| Abstract: | Objective To explore the mechanism of the immune therapy of HP specific antibody to the diseases in stomech and duodenum. Methods In several goup match of HP, HP specific antibody, stomachal fluid and complement, observe the function of kill HP in vitro. Results In pH<4, HP combined with HP specific antibody, then activate complement, eventrally result in killing HP. Conclusion To take HP spcifec antibody by oral can cure the diseases of HP infection. |
| Keywords: | helicobacter pylori helicobacter pylori specific antibody against bacteria in vitro |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |