两次检测模式检测血液病毒标志物初探

目的　了解血液病毒标志物两次检测的意义和作用。方法　调查我站2002年1月～2003年12月常规血液检测的结果,并追踪随访2次检测结果不一致的献血者,采集其6个月后的血标本复检,对可疑标本用NAT作进一步的检测。结果　2次检测不一致率为1.37%,绝大部分两次检测结果不一致的标本为假阳性。结论　两次检测并不能显著提高血液质量。应通过提高试剂总体质量和实施NAT检测来进一步提高输血安全性。

Investigation on the Mode of Double Testing of Blood for Virus Markers

Objective To study the significance and role of double testing of blood for virusmarkers.Methods The data on the results of routine blood testing at our station from January ,2002 toDecember ,2003 were gathered and analysed. The blood donors with inconsistent results during the doubletesting were followed up and their blood samples were collected at least six month later. Nucleic acidamplification testing(NAT) was performed on the samples. Results Only 1.37 % of the donors showedinconsistent results during the double testing. Most of the positive results were false positive.Conclusion The quality of the blood supply was not significantly improved by the double testing. Itis helpful to enhance blood safety further by improvement of quality of the reagents and introductionof NAT.