| CIK细胞生物学特性及抗肿瘤作用的研究进展 |
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| 引用本文： | 张志凯.CIK细胞生物学特性及抗肿瘤作用的研究进展[J].世界肿瘤杂志,2008,7(1):52-56. |
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| 作者姓名： | 张志凯 |
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| 作者单位： | 广州医学院附属肿瘤医院,生物工程室,广东,广州,510095;广州医学院附属肿瘤医院,生物工程室,广东,广州,510095 |
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| 摘 要： | CIK细胞是人外周血或脐血单个核细胞在体外经多种细胞因子刺激后获得的一群异质细胞，它增殖能力强、杀瘤活性高、不良反应少，是肿瘤过继免疫治疗中更为有效的杀瘤效应细胞。在临床上已经用于治疗多种恶性肿瘤，并且疗效确切，本文CIK细胞的生物学特性及抗肿瘤作用的研究情况做一综述。
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| 关 键 词： | CIK细胞 生物学特性 肿瘤 |
Advance in biological features and anti-tumor activity of cytokine-induced killer cells |
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| Institution: | ZHANG Zhi-kai, QI Yan-chao (Department of Bioengineering, the Affiliated Tumor Hospital of Guangzhou Medical College, Guang zhou, 510095, China) |
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| Abstract: | Cytokine-induced killer （CIK） cells are a cluster of alloplasm cells, which are prepared from the mononuclear cells of human peripheral blood or cord blood that might be stimulated by some kinds of cytokines. The proliferation and cytotoxicity of CIK cells are high, and the side effect is low. CIK cell is a more effective anti-tumor effector cell in adoptive immunotherapy. It has been used to treat many malignant tumors. This paper reviews the advance of biological features and anti-tumor activity of CIK cells. |
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| Keywords: | cytokine-induced killer cells biological features tumor |
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