| 邻苯二甲酸二丁酯对果蝇生育力和寿命影响 |
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| 引用本文： | 张欣文,丁晓晨,张前龙,周晓欢,张波,蔡干慧,徐思红. 邻苯二甲酸二丁酯对果蝇生育力和寿命影响[J]. 中国公共卫生, 2007, 23(3): 303-304 |
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| 作者姓名： | 张欣文 丁晓晨 张前龙 周晓欢 张波 蔡干慧 徐思红 |
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| 作者单位： | 1. 同济大学医学院预防医学教研室,上海,200092
2. 上海市黄浦区疾病预防控制中心 |
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| 摘 要： | 目的研究邻苯二甲酸二丁酯（DBP）对果蝇生育力和寿命的毒性作用。方法将果蝇随机分为4组，分别给予含DBP为0，0．2％，0．6％和1．8％的培养基喂饲，雌雄配对产子，每日观察并记录子代孵化数和亲代存活数。结果各染毒组果蝇不育的比例高于对照组，1．8％浓度组果蝇的平均生育数显著低于对照组（P〈0．05）；随着DBP浓度的增加，雌蝇平均产卵期逐渐缩短；雌雄果蝇的平均寿命也逐渐缩短。结论DBP干扰了果蝇正常的生长发育和新陈代谢，使其生育能力降低，并加速其衰老。
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| 关 键 词： | 邻苯二甲酸二丁酯 生育力 寿命 果蝇 |
| 文章编号： | 1001-0580(2007)03-0303-02 |
| 修稿时间： | 2006-07-07 |
Effects of dibutyl phthalate on fecundity and life span of drosophila melanogaster |
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| ZHANG Xin- wen , DING Xiao-chen , ZHANG Qian-long, et al. Effects of dibutyl phthalate on fecundity and life span of drosophila melanogaster[J]. Chinese Journal of Public Health, 2007, 23(3): 303-304 |
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| Authors: | ZHANG Xin- wen DING Xiao-chen ZHANG Qian-long et al |
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| Affiliation: | Department of Preventive Medicine, Medical College, Tongji University ,Shanghai 200092, China |
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| Abstract: | Objective To study the effects of di-n-butyl phthalate(DBP) on the fecundity and the life span in drosophila melanogaster.Methods Drosophila melanogasters were divided randomly into four groups and were continuously fed with medium containing 0%,0.2%,0.6%,1.8% DBP during entire trial period.The eclosion numbers of filial generation flies and the surviving numbers of parent flies were observed and recorded daily.Results The percent of sterility of drosophilas in DBP groups were higher than that in control group;the average reproduction of flies in 1.8% DBP group was observably reduced as compared with control group(P<0.05).The average proreation days and the average life span of flies in DBP groups were gradually shortened with the rise of DBP concentration.Conclusion DBP can interfer flies' natural development and metabolism;reduce flies' fecundity;shorten flies' life span obviously in some degree. |
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| Keywords: | di-n-butyl phthalate(DBP) fecundity life span drosophila melanogaster |
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