Somatostatin in gastric juice in normal subjects and patients with duodenal ulcer |
| |
| Authors: | Dr. Koji Sumii MD Masaaki Sumioka MD Masaharu Yoshihara MD Akira Tari MD Ken Haruma MD Goro Kajiyama MD |
| |
| Affiliation: | (1) First Department of Internal Medicine, Hiroshima University School of Medicine, 1-2-3, Kasumi Minami-ku, 734 Hiroshima, Japan |
| |
| Abstract: | Somatostatin in gastric juice was determined in normal subjects and patients with duodenal ulcer. Gel exclusion chromatography of gastric juice revealed that the main immunoreactivity existed at the position of somatostatin-14. A large amount of somatostatin was present in gastric juice, and the quantity increased following tetragastrin stimulation. Furthermore, there was a good inverse correlation between somatostatin concentration and acidity of gastric juice; however, there was no difference between normal subjects and patients with duodenal ulcer in the amount of somatostatin released into gastric juice. |
| |
| Keywords: | somatostatin gastric juice duodenal ulcer |
| 本文献已被 SpringerLink 等数据库收录！ |
