Screening of plants used in Danish folk medicine to treat epilepsy and convulsions |
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| Authors: | Jäger Anna K Gauguin Bente Adsersen Anne Gudiksen Lene |
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| Affiliation: | Department of Medicinal Chemistry, The Danish University of Pharmaceutical Sciences, 2 Universitetsparken, 2100 Copenhagen O, Denmark. ankj@dfuni.dk |
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| Abstract: | Aqueous and ethanolic extracts of 42 plants used in Danish folk medicine for the treatment of epilepsy and convulsions, or for inducing sedation, were tested for affinity to the GABA(A)-benzodiazepine receptor in the flumazenil-binding assay. Ethanolic extracts of leaves of Primula elatior and Primula veris and aerial parts of Tanacetum parthenium exhibited good, dose-dependent affinity. |
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