经皮注射平阳霉素碘油乳剂治疗肝海绵状血管瘤

目的：探讨CT引导下经皮注射平阳霉素碘油乳剂治疗肝海绵状血管瘤的疗效及安全性。方法：选择肝海绵状血管瘤患者34例，瘤体直径为3．2～12．0cm，采用CT引导下经皮穿刺，注射平阳霉素碘油乳剂治疗肝海绵状血管瘤，注射剂量为6～20ml。所有病例术后3个月、半年、1年各复查CT1次。结果：经皮注射平阳霉素碘油乳剂后，29例血管瘤瘤体内碘油沉积良好，5例PLE不能完全充盈瘤灶。术后3～6个月，全部病例瘤体均有明显缩小，其中缩小达80％以上者18例，〉50％者14例，缩小〈50％者2例。本组病例未出现肝脏坏死、胆管毁损、胆囊坏死穿孔、急性胰腺炎等严重并发症。结论：经皮注射平阳霉素碘油乳剂治疗肝海绵状血管瘤是一种操作简便且安全高效的治疗方法。

Treatment of Cavernous Hemangiomas of Liver by Percutaneous Intratumoral Pingyangmycin Lipiodol Emulsion Injection

Objective：To assess the safety and effectiveness of treatment of cavernous hemangiomas of liver （CHL） by percutaneous intratumoral pingyangmycin lipiodol emulsion （PLE） under CT guidance. Methods：34 cases of cavernous hemangioma of liver underwent CT guided percutaneous pingyangmycin lipiodol emulsion multi point injection,with a dosage of 6-20ml depending on the size of the tumor which varied from 3.2-12.0cm. Each case undertook upper abdominal CT scan 3 months later,and then with 6 month to 1 year periodic follow-up. Results：The tumors in 29 cases were fully filled with PLE,and the lesions in 5 cases were not fully filled with lipiodol. All the tumors decreased in volume markedly 3 months to 6 months after the therapy,The sizes of the tumors were decreased more than 80% in 18 cases,more than 50G in 14 cases,and less than 50% in 2 cases. There were no severe complications in this series. Conclusion： Percutaneous intratumoral injection of PLE to treat cavernous hamangioma of liver is a safe and effective method.