| 慢性粒细胞白血病骨髓染色体核型异常的结果分析 |
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| 引用本文： | 吴敏华,容伯芬,陈妙婵. 慢性粒细胞白血病骨髓染色体核型异常的结果分析[J]. 广州医药, 2011, 42(1): 60-61. DOI: 10.3969/j.issn.1000-8535.2011.01.029 |
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| 作者姓名： | 吴敏华 容伯芬 陈妙婵 |
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| 作者单位： | 广东省佛山市第一人民医院输血科,528000 |
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| 摘 要： | 目的 探讨慢性粒细胞白血病(CML)患者骨髓细胞染色体核型变化的意义.方法 采用骨髓细胞短期培养法, 应用R显带技术对CML患者进行骨髓染色体核型分析.结果 67例CML患者中62例检出费城染色体Ph,阳性率为92.5%,其中有12例除Ph阳性外还合并数目异常及结构异常.结论 对CML患者进行细胞遗传学动态观察对病情进...
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| 关 键 词： | 慢性粒细胞白血病 染色体核型 异常 |
Analysis of bone marrow chromosome aberration in chronic myelogenous leukemia |
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| Wu Minhua,Rong Bofen,Chen Miaochan. Analysis of bone marrow chromosome aberration in chronic myelogenous leukemia[J]. Guangzhou Medical Journal, 2011, 42(1): 60-61. DOI: 10.3969/j.issn.1000-8535.2011.01.029 |
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| Authors: | Wu Minhua Rong Bofen Chen Miaochan |
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| Affiliation: | Wu Minhua,Rong Bofen,Chen Miaochan.The First People's Hospital of Foshan,Guangdong,528000,China |
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| Abstract: | Objective To investigate the clinical significance of bone marrow chromosome aberration in Chronic myelogenous leukemia(CML).Methods Chromosome specimens were prepared by short-term culture of bone marrow cells and karyotype.Analysis were carried out using R-banding techniques in CML.Results 67 patients,in which 62(92.5%)patients were Ph chromosome positive while 12(7.5%)patients were Ph chromosome negative,were investigated.The 12 cases not only Ph chromosome positive but also chromosome aberration.Conclus... |
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| Keywords: | Chronic myelogenous leukemia(CML) Chromosome karyotype Aberration |
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