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结构脂肪乳和中长链脂肪乳临床副作用比较
引用本文:俞亚红,杨继鑫. 结构脂肪乳和中长链脂肪乳临床副作用比较[J]. 临床外科杂志, 2008, 16(12): 811-812
作者姓名:俞亚红  杨继鑫
作者单位:华中科技大学同济医学院附属同济医院外科,武汉,430030;华中科技大学同济医学院附属同济医院外科,武汉,430030
摘    要:目的观察和比较结构脂肪乳(sTG)和传统中/长链脂肪乳(MCT/LCT 1:1)临床副作用,以减少肠外营养并发症的发生。方法选择我科50例需要进行中等腹部手术且术前ALT和AST均正常的患者,随机分为实验组和对照组,术后连续5d分别给于结构脂肪乳(力文。)和中/长链脂肪乳(力能。)进行肠外营养,分别观察两组患者副反应(恶心呕吐、头痛、发热)和肝功能指标(ALT、AST)。结果实验组与对照组的患者恶心、呕吐的发生率分别为44%与72%,头痛的发生率分别为40%与68%,发热的发生率分别为36%与64%;实验组与对照组ALT及AST均在正常范围内,实验组均低于对照组,ALT分别为(24±0.25)U/L与(28±0.35)U/L,AST分别为(20±0.19)U/L与(26±0.31)U/L。结论结构脂肪乳较传统中/长链脂肪乳的副作用小,两种脂肪乳制剂均不造成肝脏功能的明显损害。

关 键 词:结构脂肪乳  中/长链脂肪乳  副作用

Comparison of clinical side effects of structured lipid and MCT/LCT
YU Ya-hong,YANG Ji-xin. Comparison of clinical side effects of structured lipid and MCT/LCT[J]. Journal of Clinical Surgery, 2008, 16(12): 811-812
Authors:YU Ya-hong  YANG Ji-xin
Affiliation:YU Ya-hong,YANG Ji-xin.(Department of Surgery,Tongji Hospital of Tongji Medical College,Huazhong University of Science , Technology,Wuhan 430030,China)
Abstract:Objective To observe and compare clinical side effects of structured lipid and traditional MCT/LCT in order to reduce complications of TPN.Methods Fifteen patients who were to ready to accept middle-sized abdominal operations with normal level of ALT and AST were chosen,and randomly divided into two groups:structured lipid was given to experimental group,and MCT/LCT was given to the control for 5 days after operation.The side effects(including nausea/vomiting,headache and fever) and liver function(including...
Keywords:structured lipid  MCT/LCT  side effect  
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