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| 高山红景天提取物对糖尿病大鼠谷胱甘肽过氧化物酶活性及丙二醛含量的影响 | |
| 引用本文： | 崔雄,朴锦花,刘宇,全信福.高山红景天提取物对糖尿病大鼠谷胱甘肽过氧化物酶活性及丙二醛含量的影响[J].时珍国医国药,2007,18(9):2142-2143. |
| 作者姓名： | 崔雄 朴锦花 刘宇 全信福 |
| 作者单位： | 1. 延边大学医院,吉林,延吉,133000 2. 延边大学药学院,吉林,延吉,133000 3. 延边大学福祉医院,吉林,延吉,133002 |
| 基金项目： | 吉林省中医药管理局基金资助项目（No.2006zy025） |
| 摘 要： | 目的观察高山红景天提取物对链脲佐菌素(STN)诱导的糖尿病大鼠肝组织中的谷胱甘肽过氧化物酶(glutathione peroxidase,GSH-Px)活性及丙二醛(malodialdehyde,MDA)含量的影响。方法采用链脲佐菌素诱导糖尿病大鼠模型,分别测定各组大鼠使用高山红景天提取物处理前后大鼠肝组织中GSH-Px活性和MDA含量。结果高山红景天提取物可提高糖尿病大鼠肝组织中的GSH-Px活性,降低MDA含量。结论高山红景天提取物对糖尿病大鼠具有清除自由基及抗脂质过氧化作用。 |
| 关 键 词： | 红景天提取物 糖尿病 谷胱甘肽过氧化物酶 丙二醛 抗氧化作用 |
| 文章编号： | 1008-0805（2007）09-2142-01 |
| 收稿时间： | 2007-02-13 |
| 修稿时间： | 2007-05-16 |
Effects of Rhodiola sachalinensis Aqueous Extract on the Activity of GSH-Px and the Content of MDA in Diabetic Rats |
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| CUI Xiong,PIAO Jin-hua,LIU Yu,QUAN Xin-fu.Effects of Rhodiola sachalinensis Aqueous Extract on the Activity of GSH-Px and the Content of MDA in Diabetic Rats[J].Lishizhen Medicine and Materia Medica Research,2007,18(9):2142-2143. | |
| Authors: | CUI Xiong PIAO Jin-hua LIU Yu QUAN Xin-fu |
| Institution: | 1. Yanbian University Hospital, Yanji 133000, Jilin, China; 2. College of Pharmacy, Yanbian University, Yanji 133000, Jilin, China ; 3. Yanbian University, Fuzhi Hospital, Yanji, Jilin 133002, China |
| Abstract: | Objective To observe the effects of Rhodiola sachalinsis A.Bur aqueous extract (RSE) on the activity of GSH-Px and the content of MDA in streptozotocin(STZ)-induced diabetic rats.Methods The diabetic model of rat was induced by STZ. The activity of GSH-Px and the content of MDA were measured before and after treatment with RSE.Results RSE increased the hepatic GSH-Px activity and decreased the content of MDA.Conclusion RSE can clear the free radicals and has the effect of anti -lipid peroxidation. |
| Keywords: | Rhodiola sachalinensis Diabetes Glutathione peroxidase Malondialdehyde Antioxidation |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |