Sodium valproate in Huntington's chorea. |
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Authors: | B K Tan H J Leijnse-Ybema M F Zee |
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Abstract: | In a single-case study of Huntington's Chorea the effect of sodium valproate on motor behaviour was first compared with that of L-Dopa and than investigated further alone. Drug effect was assessed in terms of number of EMG-bursts with concurrent determinations of serum-levels of sodium valproate. The main result of this study was the development of a state of tolerance to sodium valproate. |
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