胎心监护评估86例ICP孕妇的围产儿预后分析

目的探讨胎心监护评估妊娠期肝内胆汁淤积症（ICP）患者胎儿窘迫的临床意义及对围产儿的影响。方法用SRF61885电子监护仪监护86例ICP单胎患者，同时随机抽选同期住院分娩无妊娠并发症的单胎孕妇120例为正常对照，比较分析两组孕妇无刺激实验结果、分娩方式、围产儿预后情况。结果ICP组胎心监护异常率、剖宫产率、围产儿预后不良率明显高于对照组（X^2值分别为74．184、138．487、8．882，均P〈0．05）。两组孕妇无刺激实验异常患者围产儿预后不良率均明显高于正常患者（X^2值分别为11．098、21．845，均P〈0．05）。两组均无围产儿死亡病例。结论加强对ICP孕妇孕晚期胎心监护，及早发现隐性胎儿窘迫的发生．适时终止妊娠，可以明显改善ICP围产儿预后。

Analysis of fetal heart rate monitoring to assess the perinatal outcome of 86 cases of ICP women

Objective To explore the clinical significance of fetal heart rate monitoring in assessing fetal distress in patients with intrahepatic cholestasis of pregnancy （ICP） and the impact on perinatal outcome. Methods Eighty-six patients with singleton pregnancy were monitored by Sunray SRF618B5 electronic monitor, and 120 cases of hospitalized singleton pregnancy without any complications were randomly selected over the same period as controls. NST results, delivery mode and perinatal outcome were analyzed and compared between two groups. Results The abnormal rate of fetal heart, cesarean section rate and the rate of unfavorable perinatal prognosis of ICP group were significantly higher than those of control group （X2Value was 74. 184, 138. 487 and 8. 882, respectively, all P 〈 0.05）. The rate of unfavorable prognosis of patients with abnormal NST results in two groups was significantly higher than that in normal patients （X^2value was 11. 098 and 21. 845, respectively, both P 〈 0.05）. There was no perinatal death. Conclusion Strengthening fetal heart rate monitoring of ICP women in the third trimester, early detecting the incidence of hidden fetal distress and timely terminating pregnancy can improve ICP perinatal outcomes significantly.