Limb salvage surgery in combination with brachytherapy and external beam radiation for high-grade soft tissue sarcomas |
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| Authors: | G. Beltrami,H.A. Rü diger,M.M. Mela,G. Scoccianti,L. Livi,A. Franchi,D.A. Campanacci,R. Capanna |
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| Affiliation: | 1. Department of Orthopaedic Oncology, University of Florence, Careggi, Florence, Italy;2. Department of Orthopaedics, University of Zurich, Balgrist, Forchstrasse 340, 8008 Zurich, Switzerland;3. Department of Medical Oncology, University of Florence, Careggi, Florence, Italy;4. Department of Radiotherapy, University of Florence, Careggi, Florence, Italy;5. Department of Pathology, University of Florence, Careggi, Florence, Italy |
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| Abstract: | While combined treatment of high-grade soft tissue sarcoma with resection and radiotherapy has become an accepted standard, outlines of treatment algorithms remain a matter of debate. Our institutional practice foresees wide surgical resection with adjuvant brachytherapy and external beam radiation. It was the purpose of this study to determine long-term outcome, prognostic factors for local and systemic recurrence and morbidity in patients with high-grade soft tissue sarcomas of the extremities, who were subjected to this regimen. |
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| Keywords: | Soft tissue sarcoma Brachytherapy Limb salvage surgery Radiation Orthopaedics Oncology Radiotherapy Soft tissue reconstruction |
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